Just starting to use Disqus for blog comments, any tips?

I've just enabled Disqus on my blog (running Drupal 6) here, and would love to hear any tips on using it and encouraging people to use it. I see these huge Disqus comment threads sometimes and am wondering if that's happening because the blogs are just incredibly popular and well connected or because there's some secret sauce that Disqus adds if you do the right things with it.

So, I'd love any input as to how any of you might be using it, and if it helps in any particular way to build a solid readership that typical comments might not provide.

Thank you!